Mouse Monoclonal Antibody to HTR3A

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/100 - 1/500; FCM: 1/200 - 1/400; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4D5E7
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human HTR3A (AA: extra 24-157) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 55.3kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4444
Reference: 1.PLoS One. 2015 Dec 23;10(12):e0145269.2.Iran J Allergy Asthma Immunol. 2014 Feb;13(1):33-9.

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