Mouse Monoclonal Antibody to CD207

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1C5A1
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human CD207 (AA: extra 155-328) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 36.7kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4487
Reference: 1.Immunol Cell Biol. 2015 Oct;93(9):815-24.2.J Immunol. 2011 Feb 1;186(3):1377-83.

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