Anti-Sox-10 Monoclonal Antibody

Anti-Sox-10 Monoclonal Antibody


Regular price $100.00 You Pay

Supplier: GenomeMe


SRY (Sex Determining Region Y)-Box 10 (SOX-10), also known as transcription factor SOX-10, is a nuclear transcription factor that acts in regulation of embryonic development and in the specification and differentiation of cells of melanocytic lineage. SOX-10 is diffusely expressed in neurofibromas and schwannomas, and mutations in the SOX-10 gene are linked to Waardenburg-Shah and Waardenburg-Hirschsprung disease. Anti-SOX-10 has been shown to be sensitive for conventional, spindled, and desmoplastic melanoma, and has been used to detect metastatic melanoma and nodal capsular nevus in sentinel lymph nodes.


Clone IHC010
Source Mouse Monoclonal
Positive Control Melanoma, Skin Melanocytes
Dilution Range 1:100 - 1:200


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