Product Type: Antibody
Descritpion: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
Research Areas: Cancer, Signal transduction, Stem cells
Recommended Dilutions: WB 1:200-1:1000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC000254
Immunogen: Recombinant protein of human ACVR1B
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 57kDa
Tissue Specificity/Positive Control: Expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.