ADD1 Polyclonal AntibodyE-AB-10034
Product Type: Antibody
Descritpion: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Research Areas: Cancer, Signal transduction, Tags & Cell Markers
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC013393
Immunogen: Recombinant protein of human ADD1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit.
Cellular Localization: Cytoplasm>cytoskeleton. Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-add1_polyclonal_antibody-30094.html
Manual Link: https://www.elabscience.com/viewpdf-30094-elabscience-E-AB-10034.PDF