CASP2 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Research Areas: Cancer, Cell Biology, Metabolism
Applications: WB,ELISA
Recommended Dilutions: WB 1:1000-1:5000
Size: 200 uL
Concentration: 0.4mg/mL
Swissprot: P42575
Gene Accession: BC002427
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human CASP2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 51kDa
Tissue Specificity/Positive Control: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Cellular Localization: Cytosol,Mitochondrion,Nucleus,Other locations:cytoplasm,membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-casp2_polyclonal_antibody-30110.html
Manual Link: https://www.elabscience.com/viewpdf-30110-elabscience-E-AB-10051.PDF