CASP6 Polyclonal Antibody

CASP6 Polyclonal Antibody

E-AB-10052

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Research Areas: Cancer, Cell Biology, Metabolism, Neuroscience
Applications: WB,ELISA
Recommended Dilutions: WB 1:200-1:1000
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: P55212
Gene Accession: BC000305
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human CASP6
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 33kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-casp6_polyclonal_antibody-30111.html
Manual Link: https://www.elabscience.com/viewpdf-30111-elabscience-E-AB-10052.PDF