MMP13 Polyclonal Antibody
MMP13 Polyclonal Antibody

MMP13 Polyclonal Antibody

E-AB-10064

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Research Areas: Cancer, Cell Biology, Cardiovascular, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:10-1:50
Size: 200 uL
Concentration: 0.4mg/mL
Swissprot: P45452
Gene Accession: BC067522
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human MMP13
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 54kDa
Tissue Specificity/Positive Control: Seems to be specific to breast carcinomas.
Cellular Localization: Secreted>extracellular space>extracellular matrix.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-mmp13_polyclonal_antibody-30123.html
Manual Link: https://www.elabscience.com/viewpdf-30123-elabscience-E-AB-10064.PDF