IkB alpha Polyclonal Antibody
IkB alpha Polyclonal Antibody

IkB alpha Polyclonal Antibody

E-AB-10086

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. 
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:200-1:1000, IHC 1:15-1:50
Size: 200 uL
Concentration: 0.1mg/mL
Swissprot: P25963
Gene Accession: BC004983
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human NFKBIA
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 36kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-ikb_alpha_polyclonal_antibody-30145.html
Manual Link: https://www.elabscience.com/viewpdf-30145-elabscience-E-AB-10086.PDF