APIP Polyclonal Antibody
APIP Polyclonal Antibody

APIP Polyclonal Antibody

E-AB-10089

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.
Research Areas: Cell Biology
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:200-1:1000, IHC 1:25-1:100
Size: 200 uL
Concentration: 0.2mg/mL
Swissprot: Q96GX9
Gene Accession: BC008440
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human APIP
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 27kDa
Tissue Specificity/Positive Control: Ubiquitously expressed with high expression in skeletal muscle, heart and kidney.
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-apip_polyclonal_antibody-30148.html
Manual Link: https://www.elabscience.com/viewpdf-30148-elabscience-E-AB-10089.PDF