Product Type: Antibody
Descritpion: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Research Areas: Cancer, Cell Biology
Recommended Dilutions: WB 1:1000-1:5000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC004431
Immunogen: Recombinant protein of human BAK1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 23kDa
Tissue Specificity/Positive Control: Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Cellular Localization: Mitochondrion membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.