IL11RA Polyclonal Antibody

E-AB-10100

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.
Research Areas: Cancer, Immunology, Stem cells
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Concentration: 0.5mg/mL
Swissprot: Q14626
Gene Accession: BC003110
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human IL11RA
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 45kDa
Tissue Specificity/Positive Control: Expressed in a number of cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-il11ra_polyclonal_antibody-30159.html
Manual Link: https://www.elabscience.com/viewpdf-30159-elabscience-E-AB-10100.PDF