AMACR Polyclonal Antibody
AMACR Polyclonal Antibody

AMACR Polyclonal Antibody

E-AB-10127

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Research Areas: Cell Biology, Metabolism, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:25-1:100
Size: 200 uL
Concentration: 0.1mg/mL
Swissprot: Q9UHK6
Gene Accession: BC009471
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human AMACR
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 42kDa
Tissue Specificity/Positive Control:
Cellular Localization: Peroxisome. Mitochondrion.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-amacr_polyclonal_antibody-30184.html
Manual Link: https://www.elabscience.com/viewpdf-30184-elabscience-E-AB-10127.PDF