FGF12 Polyclonal AntibodyE-AB-10181
Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [
Research Areas: Cardiovascular, Signal transduction
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Gene Accession: BC022524
Immunogen: Recombinant protein of human FGF12
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 20kDa
Tissue Specificity/Positive Control: Brain, eye and testis; highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and in a segmental pattern of the body wall; in adult olfactory bulb, less in cerebellum, deep cerebellar nuclei, cortex and multiple midbrain structures.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-fgf12_polyclonal_antibody-30236.html
Manual Link: https://www.elabscience.com/viewpdf-30236-elabscience-E-AB-10181.PDF