Product Type: Antibody
Descritpion: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.
Research Areas: Cardiovascular, Immunology
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC109215
Immunogen: Recombinant protein of human F9
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Synthesized primarily in the liver and secreted in plasma.
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-factor_ix_polyclonal_antibody-30684.html
Manual Link: https://www.elabscience.com/viewpdf-30684-elabscience-E-AB-10639.PDF