TGM2 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Cell Biology, Metabolism, Immunology, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:200-1:1000, IHC 1:15-1:50
Size: 200 uL
Concentration: 0.1mg/mL
Swissprot: P21980
Gene Accession: BC003551
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human TGM2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 77kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytosol,Endoplasmic reticulum,endoplasmic reticulum,Extracellular region or secreted,extracellular exosome,extracellular matrix,Mitochondrion,Plasma Membrane,intrinsic component of plasma membrane,Other locations:focal adhesion
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-tgm2_polyclonal_antibody-30689.html
Manual Link: https://www.elabscience.com/viewpdf-30689-elabscience-E-AB-10644.PDF