CD218b Polyclonal AntibodyE-AB-10677
Product Type: Antibody
Descritpion: Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiationw218b), is a human gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-?B and MAPK8 (JNK) in response to IL18.
Research Areas: Cancer, Immunology
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Gene Accession: BC106765
Immunogen: Recombinant protein of human IL18RAP
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 68kDa
Tissue Specificity/Positive Control: Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-cd218b_polyclonal_antibody-30722.html
Manual Link: https://www.elabscience.com/viewpdf-30722-elabscience-E-AB-10677.PDF