CNN3 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Research Areas: Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:50-1:200
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: Q15417
Gene Accession: BC025372
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human CNN3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 36kDa
Tissue Specificity/Positive Control: Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.
Cellular Localization: Cytoskeleton,actin cytoskeleton,Cytosol,Other locations:cell-cell adherens junction,dendritic spine,focal adhesion,neuronal cell body,postsynaptic density
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-cnn3_polyclonal_antibody-30755.html
Manual Link: https://www.elabscience.com/viewpdf-30755-elabscience-E-AB-10711.PDF