ACTN3 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants. The reference genome contains the non-coding allele. The non-functional allele of this gene is associated with elite athlete status.
Research Areas: Cancer, Signal transduction
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Concentration: 0.2mg/mL
Swissprot: Q08043
Gene Accession: BC099647
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human ACTN3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 103kDa
Tissue Specificity/Positive Control: Expressed only in a subset of type 2 skeletal muscle fibers.
Cellular Localization: Cytoskeleton,actin filament,Cytosol,Extracellular region or secreted,extracellular exosome,Other locations:focal adhesion,intracellular,pseudopodium
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-actn3_polyclonal_antibody-30767.html
Manual Link: https://www.elabscience.com/viewpdf-30767-elabscience-E-AB-10723.PDF