AKAP9 Polyclonal AntibodyE-AB-10758
Product Type: Antibody
Descritpion: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3.
Research Areas: Cancer, Tags & Cell Markers
Recommended Dilutions: IHC 1:10-1:50
Size: 200 uL
Immunogen: Recombinant protein of human AKAP9
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Widely expressed. Isoform 4 is highly expressed in skeletal muscle and in pancreas.
Cellular Localization: Cytoplasm. Cytoplasm>cytoskeleton>centrosome. Golgi apparatus. Cytoplasmic in parietal cells.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-akap9_polyclonal_antibody-30802.html
Manual Link: https://www.elabscience.com/viewpdf-30802-elabscience-E-AB-10758.PDF