Product Type: Antibody
Descritpion: Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC045609
Immunogen: Recombinant protein of human AMBRA1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasmic vesicle>autophagosome.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ambra1_polyclonal_antibody-30831.html
Manual Link: https://www.elabscience.com/viewpdf-30831-elabscience-E-AB-10787.PDF