Product Type: Antibody
Descritpion: The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
Research Areas: Cell Biology
Recommended Dilutions: IHC 1:100-1:300
Size: 200 uL
Gene Accession: BC008877
Immunogen: Recombinant protein of human CARD9
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-card9_polyclonal_antibody-31075.html
Manual Link: https://www.elabscience.com/viewpdf-31075-elabscience-E-AB-11032.PDF