TBXAS1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Concentration: 0.7mg/mL
Swissprot: P24557
Gene Accession: BC014117
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human TBXAS1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.
Cellular Localization: Endoplasmic reticulum membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-tbxas1_polyclonal_antibody-31169.html
Manual Link: https://www.elabscience.com/viewpdf-31169-elabscience-E-AB-11128.PDF