Product Type: Antibody
Descritpion: Eukaryotic translation initiation factor 3 subunit H is a protein that in humans is encoded by the EIF3H gene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Research Areas: Epigenetics and Nuclear Signaling
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC000386
Immunogen: Recombinant protein of human EIF3H
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-eif3h_polyclonal_antibody-31223.html
Manual Link: https://www.elabscience.com/viewpdf-31223-elabscience-E-AB-11182.PDF