Product Type: Antibody
Descritpion: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
Research Areas: Cell Biology
Recommended Dilutions: IHC 1:100-1:300
Size: 200 uL
Gene Accession: BC011902
Immunogen: Recombinant protein of human FGFR1OP
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas.
Cellular Localization: Cytoskeleton,centriole,centrosome,Cytosol,Nucleus,Other locations:cell projection,perinuclear region of cytoplasm
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-fgfr1op_polyclonal_antibody-31272.html
Manual Link: https://www.elabscience.com/viewpdf-31272-elabscience-E-AB-11232.PDF