Product Type: Antibody
Descritpion: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300
Size: 200 uL
Gene Accession: BC003583
Immunogen: Recombinant protein of human FTO
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 58kDa
Tissue Specificity/Positive Control: Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary.
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-fto_polyclonal_antibody-31288.html
Manual Link: https://www.elabscience.com/viewpdf-31288-elabscience-E-AB-11248.PDF