Product Type: Antibody
Descritpion: This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14.
Research Areas: Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC012109
Immunogen: Recombinant protein of human HOMER2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Cytoplasm. Cell junction>synapse>postsynaptic cell membrane>postsynaptic density. Cell junction>synapse. Postsynaptic density of neuronal cells. The stabilization and clustering of the metabotropic glutamate receptors appears to be mediated by isoform 1 and isoform 2 at the cell surface.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-homer2_polyclonal_antibody-31337.html
Manual Link: https://www.elabscience.com/viewpdf-31337-elabscience-E-AB-11297.PDF