Product Type: Antibody
Descritpion: 17?-HSD2 (17? hydroxysteroid dehydrogenase type 2) belongs to the 17?-HSD family of proteins that regulate the availability of steroids within a tissue. 17?-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17?-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC009581
Immunogen: Recombinant protein of human HSD17B2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 43kDa
Tissue Specificity/Positive Control:
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-hsd17b2_polyclonal_antibody-31344.html
Manual Link: https://www.elabscience.com/viewpdf-31344-elabscience-E-AB-11304.PDF