IKBKE Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:200-1:1000, IHC 1:50-1:200
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: Q14164
Gene Accession: BC107812
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human IKBKE
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 80kDa
Tissue Specificity/Positive Control: Highly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta. Weakly expressed in lung, kidney, prostate, ovary and colon.
Cellular Localization: Cytoplasm. Nucleus. Nucleus>PML body. Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-ikbke_polyclonal_antibody-31363.html
Manual Link: https://www.elabscience.com/viewpdf-31363-elabscience-E-AB-11323.PDF