JMJD6 Polyclonal AntibodyE-AB-11340
Product Type: Antibody
Descritpion: This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Developmental biology, Immunology, Stem cells
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Gene Accession: BC066654
Immunogen: Recombinant protein of human JMJD6
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 46kDa
Tissue Specificity/Positive Control: Highly expressed in the heart, skeletal muscle and kidney. Expressed at moderate or low level in brain, placenta, lung, liver, pancreas, spleen, thymus, prostate, testis and ovary. Up-regulated in many patients with chronic pancreatitis. Expressed in nursing thymic epithelial cells.
Cellular Localization: Nucleus>nucleoplasm. Nucleus>nucleolus. Mainly found throughout the nucleoplasm outside of regions containing heterochromatic DNA, with some localization in nucleolus. During mitosis, excluded from the nucleus and reappears in the telophase of the cell cycle.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-jmjd6_polyclonal_antibody-31380.html
Manual Link: https://www.elabscience.com/viewpdf-31380-elabscience-E-AB-11340.PDF