CD44 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.
Research Areas: Cancer, Immunology, Stem cells
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:1000-1:5000, IHC 1:50-1:200
Size: 200 uL
Concentration: 0.4mg/mL
Swissprot: P16070
Gene Accession: BC004372
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human CD44
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 82kDa
Tissue Specificity/Positive Control: Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
Cellular Localization: Membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-cd44_polyclonal_antibody-31404.html
Manual Link: https://www.elabscience.com/viewpdf-31404-elabscience-E-AB-11364.PDF