Product Type: Antibody
Descritpion: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis.
Research Areas: Cell Biology
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC014904
Immunogen: Recombinant protein of human PIDD1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Ubiquitous.
Cellular Localization: Cytosol,Golgi apparatus,Golgi apparatus,Nucleus,nucleoplasm,nucleus,Other locations:cytoplasm
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pidd1_polyclonal_antibody-31409.html
Manual Link: https://www.elabscience.com/viewpdf-31409-elabscience-E-AB-11369.PDF