Product Type: Antibody
Descritpion: N-acetyltransferase 10 is an enzyme that in humans is encoded by the NAT10 gene. Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC035558
Immunogen: Recombinant protein of human NAT10
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 116kDa
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus>nucleolus. Nucleolar in interphase and redistributes to the perichromosomal layer and to the midbody during telophase.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-nat10_polyclonal_antibody-31460.html
Manual Link: https://www.elabscience.com/viewpdf-31460-elabscience-E-AB-11420.PDF