DAN Polyclonal AntibodyE-AB-11421
Product Type: Antibody
Descritpion: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: NP_005371
Immunogen: Recombinant protein of human NBL1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Most abundant in normal lung and meningioma.
Cellular Localization: Secreted
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-dan_polyclonal_antibody-31461.html
Manual Link: https://www.elabscience.com/viewpdf-31461-elabscience-E-AB-11421.PDF