Product Type: Antibody
Descritpion: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Areas: Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
Recommended Dilutions: WB 1:1000-1:5000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC010273
Immunogen: Recombinant protein of human PAICS
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 47kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytosol,Extracellular region or secreted,extracellular exosome,Other locations:cytoplasm,membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-paics_polyclonal_antibody-31510.html
Manual Link: https://www.elabscience.com/viewpdf-31510-elabscience-E-AB-11470.PDF