Product Type: Antibody
Descritpion: This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Areas: Cancer, Cell Biology, Metabolism, Neuroscience
Recommended Dilutions: IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC014058
Immunogen: Recombinant protein of human PARL
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Mitochondrion inner membrane and Nucleus. Translocated into the nucleus by an unknown mechanism.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-parl_polyclonal_antibody-31512.html
Manual Link: https://www.elabscience.com/viewpdf-31512-elabscience-E-AB-11472.PDF