Product Type: Antibody
Descritpion: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis.
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction
Recommended Dilutions: IHC 1:30-1:150
Size: 200 uL
Gene Accession: BC014518
Immunogen: Recombinant protein of human RAN
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed in a variety of tissues.
Cellular Localization: Nucleus. Cytoplasm. Melanosome. Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ran_polyclonal_antibody-31557.html
Manual Link: https://www.elabscience.com/viewpdf-31557-elabscience-E-AB-11517.PDF