Product Type: Antibody
Descritpion: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: IHC 1:20-1:100
Size: 200 uL
Gene Accession: BC014420
Immunogen: Recombinant protein of human RASAL1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea.
Cellular Localization: Cytosol,Plasma Membrane,intrinsic component of the cytoplasmic side of the plasma membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-rasal1_polyclonal_antibody-31559.html
Manual Link: https://www.elabscience.com/viewpdf-31559-elabscience-E-AB-11519.PDF