SNX27 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. 
Research Areas: Cancer, Signal transduction
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Concentration: 0.6mg/mL
Swissprot: Q96L92
Gene Accession: BC012184
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human SNX27
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control: Expressed in cells of hematopoietic origin (at protein level).
Cellular Localization: Cytoplasm>cytosol. Early endosome. In T-lymphocytes, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-snx27_polyclonal_antibody-31636.html
Manual Link: https://www.elabscience.com/viewpdf-31636-elabscience-E-AB-11596.PDF