C3 (? chain) Polyclonal AntibodyE-AB-11635
Product Type: Antibody
Descritpion: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Research Areas: Cancer, Immunology, Signal transduction
Recommended Dilutions: WB 1:200-1:1000
Size: 200 uL
Immunogen: Synthetic peptide of human C3 (? chain)
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 70kDa
Tissue Specificity/Positive Control: Plasma.
Cellular Localization: Secreted.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-c3_(?_chain)_polyclonal_antibody-39654.html
Manual Link: https://www.elabscience.com/viewpdf-39654-elabscience-E-AB-11635.PDF