GMNN Polyclonal Antibody
GMNN Polyclonal Antibody

GMNN Polyclonal Antibody

E-AB-11640

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Applications: WB,IF,ELISA
Recommended Dilutions: WB 1:100-1:500, IF/ICC 1:50-1:100
Size: 200 uL
Concentration: 0.5mg/mL
Swissprot: O75496
Gene Accession:
Reactivity: Human
,Mouse

Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human GMNN
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 24kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytosol,Nucleus,nucleoplasm,nucleus,Other locations:cytoplasm
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-gmnn_polyclonal_antibody-39659.html
Manual Link: https://www.elabscience.com/viewpdf-39659-elabscience-E-AB-11640.PDF