VMA21 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase. Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. Associates with the V0 complex of the vacuolar ATPase (V-ATPase). MEAX is a childhood-onset disease characterized by progressive vacuolation and atrophy of skeletal muscle. It is inherited in recessive fashion, affecting boys and sparing carrier females. Onset is in childhood, and patients exhibit weakness of the proximal muscles of the lower extremities, progressing slowly to involve other skeletal muscle groups over time.
Research Areas: Cell Biology, Signal transduction
Applications: IHC,IF,ELISA
Recommended Dilutions: IHC 1:50-200, IF/ICC 1:50-1:200
Size: 200 uL
Concentration: 2.6mg/mL
Swissprot: Q3ZAQ7
Gene Accession: NP_001017980
Reactivity: Human
,Mouse

Host: Rabbit
Isotype: IgG
Immunogen: Synthetic peptide of human VMA21
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control:
Cellular Localization: Endoplasmic reticulum,endoplasmic reticulum membrane,Golgi apparatus,ER to Golgi transport vesicle membrane,Lysosome,Other locations:endoplasmic reticulum-Golgi intermediate compartment membrane,integral component of membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-vma21_polyclonal_antibody-39680.html
Manual Link: https://www.elabscience.com/viewpdf-39680-elabscience-E-AB-11661.PDF