VNN2 Polyclonal AntibodyE-AB-11665
Product Type: Antibody
Descritpion: This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Recommended Dilutions: WB 1:200-1:1000, IHC 1:50-100
Size: 200 uL
Gene Accession: NP_004656
Immunogen: Synthetic peptide of human VNN2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 59kDa
Tissue Specificity/Positive Control: Widely expressed with higher expression in spleen and blood.1 Publication
Cellular Localization: Extracellular region or secreted,extracellular region,Plasma Membrane,Other locations:anchored component of membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-vnn2_polyclonal_antibody-39684.html
Manual Link: https://www.elabscience.com/viewpdf-39684-elabscience-E-AB-11665.PDF