CD55 Polyclonal AntibodyE-AB-11756
Product Type: Antibody
Descritpion: This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
Research Areas: Cancer, Immunology
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Immunogen: Recombinant protein of human CD55
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 41kDa
Tissue Specificity/Positive Control: Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
Cellular Localization: Cell membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-cd55_polyclonal_antibody-39775.html
Manual Link: https://www.elabscience.com/viewpdf-39775-elabscience-E-AB-11756.PDF