ATXN3 Polyclonal AntibodyE-AB-11761
Product Type: Antibody
Descritpion: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Immunogen: Recombinant protein of human ATXN3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 43kDa
Tissue Specificity/Positive Control: Ubiquitous.
Cellular Localization: Nucleus matrix. Predominantly nuclear, but not exclusively, inner nuclear matrix.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-atxn3_polyclonal_antibody-39780.html
Manual Link: https://www.elabscience.com/viewpdf-39780-elabscience-E-AB-11761.PDF