HFE Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Research Areas: Cancer, Metabolism, Signal transduction, Stem cells
Applications: WB
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Concentration: 1.61mg/mL
Swissprot: Q30201
Gene Accession:
Reactivity: Human
,Mouse
,Rat

Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human HFE
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 40kDa
Tissue Specificity/Positive Control: Expressed in all tissues tested except brain.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-hfe_polyclonal_antibody-39783.html
Manual Link: https://www.elabscience.com/viewpdf-39783-elabscience-E-AB-11764.PDF