CES2 Polyclonal AntibodyE-AB-11772
Product Type: Antibody
Descritpion: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.
Research Areas: Metabolism, Signal transduction
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Immunogen: Synthetic peptide of human CES2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 62kDa
Tissue Specificity/Positive Control: Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.
Cellular Localization: Endoplasmic reticulum lumen.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ces2_polyclonal_antibody-39791.html
Manual Link: https://www.elabscience.com/viewpdf-39791-elabscience-E-AB-11772.PDF