PON2 Polyclonal AntibodyE-AB-11790
Product Type: Antibody
Descritpion: This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Immunogen: Recombinant protein of human PON2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 39kDa
Tissue Specificity/Positive Control: Widely expressed with highest expression in liver, lung, placenta, testis and heart.
Cellular Localization: Membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-pon2_polyclonal_antibody-39809.html
Manual Link: https://www.elabscience.com/viewpdf-39809-elabscience-E-AB-11790.PDF