FXN Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
Research Areas: Cancer, Metabolism, Signal transduction, Tags & Cell Markers
Applications: WB
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Concentration: 0.8mg/mL
Swissprot: Q16595
Gene Accession:
Reactivity: Human
,Mouse
,Rat

Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human FXN
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 23kDa
Tissue Specificity/Positive Control: Expressed in the heart, peripheral blood lymphocytes and dermal fibroblasts.
Cellular Localization: Cytoplasm. Mitochondrion. PubMed:18725397 reports localization exclusively in mitochondria.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-fxn_polyclonal_antibody-39824.html
Manual Link: https://www.elabscience.com/viewpdf-39824-elabscience-E-AB-11805.PDF