RPS27A Polyclonal AntibodyE-AB-11838
Product Type: Antibody
Descritpion: Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
Research Areas: Cell Biology, Epigenetics and Nuclear Signaling
Recommended Dilutions: WB 1:500-1:2000
Size: 200 uL
Immunogen: Recombinant protein of human RPS27A
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 9kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cytosolic small ribosomal subunit,Endoplasmic reticulum,endoplasmic reticulum membrane,endoplasmic reticulum quality control compartment,Endosome membrane,Extracellular region or secreted,extracellular exosome,extracellular space,Mitochondrion,mitochondrial outer membrane,Nucleus,nucleolus,nucleoplasm,nucleus,Plasma Membrane,Other locations:cytoplasm,endocytic vesicle membrane,host cell,membrane,myelin sheath,small ribosomal subunit,vesicle
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-rps27a_polyclonal_antibody-39857.html
Manual Link: https://www.elabscience.com/viewpdf-39857-elabscience-E-AB-11838.PDF